DNAble
Our patented DNAble chemistry offers user-friendly isothermal DNA amplification assays that are:
- Quick
- Sensitive
- Accurate
The first commercialized on-site GMO DNA detection method, DNAble is a simple, rapid nucleic acid amplification method similar to PCR. However, DNAble amplifies targets in a fraction of the time, with minimal equipment requirements in a non-laboratory setting.
Unlike PCR, DNAble shows little inhibitory effects from extraction samples. As a result, DNAble allows for highly specific detection, with sensitivity similar to PCR results but with minimal sample preparation.
How Does It Work?
DNAble chemistry uses a nicking enzyme and a strand displacing polymerase. These enzymes work together to achieve exponential DNA amplification and can be used for end-point quantitative results. Sequence-specific molecular beacon(s) are then employed to detect the amplified target and provide a second level of specificity.
AmpliFire
AmpliFire™ Reader
AmpliFire is a portable point-of-need instrument. Optimized for isothermal chemistry, this reader has the capability to process eight DNAble samples simultaneously. AmpliFire offers a touch screen interface, data storage and portability with a rechargeable battery. Utilizing a product-specific QR code, DNAble test protocols are simple to input, which saves time and reduces protocol selection error.